DESIGNING A PATHOGEN-FOCUSED STUDY TO ADDRESS THE HIGH UNMET MEDICAL NEED REPRESENTED BY CARBAPENEM-RESISTANT GRAM-NEGATIVE PATHOGENS – THE INTERNATIONAL, MULTICENTER, RANDOMIZED, OPEN-LABEL, PHASE 3 CREDIBLE-CR STUDY

Matteo Bassetti,1,2 Mari Ariyasu,3 Bruce Binkowitz,4 Tsutae Den Nagata,3 Roger M Echols,5 Yuko Matsunaga,4 Kiichiro Toyoizumi,4 Yohei Doi6 1Infectious Diseases Clinic, Department of Medicine, University of Udine and Azienda Sanitaria Universitaria Integrata, Udine, Italy; 2Department of Health Sciences, University of Genoa, Genoa, Italy; 3Shionogi

Aim of study is to assess different alternative approaches to acute toxicity assessment of PPP, including calculation based on the assumption of additivity and in silico methods.Acute toxicity of eight PPP, containing from 2 to 5 active ingredients (AI) pesticides and number of co-formulants was assessed.In vivo studies of acute toxicity were condu

Abstract Background Following Spinal Cord Injury (SCI), innumerable inflammatory and degenerative fluctuations appear in the injured site, and even remotely in manifold new areas of the brain.Howbeit, inflammatory, degenerative, and oscillatory changes of motor cortices have been demonstrated to be due to SCI, according to recent studies confirming

Traffic congestion is a chronic problem of Bangkok.Similar to other metropolises, the city perpetually seeks for alternatives to road travel.Mass rapid transit seems to be the only way out that is expected to mitigate traffic congestion in the city.However, without common fare Mug system, travelers need to pay an initial entrance fee every time the

Introduction: Urinary incontinence is one of the most common problems among women that has significant effects on various aspects of their lives.The aim of this study was to investigate the prevalence of urinary incontinence and risk factors in women aged 40-60 years referred to urology clinics affiliated to Shahid Downlights Sadoughi University in